Section: Application Domains

Co-segmentation and Co-registration of Subcortical Brain Structures

Paticipants: Enzo Ferrante, Nikos Paragios, Iasonas Kokkinos

New algorithms to perform co-segmentation and co-registration of subcortical brain structures on MRI images were investigated in collaboration with Ecole Polytechnique de Montreal and the Sainte-Justine Hospital Research Center from Montreal [40]. Brain subcortical structures are involved in different neurodegenerative and neuropsychiatric disorders, including schizophrenia, Alzheimers disease, attention deficit, and subtypes of epilepsy. Segmenting these parts of the brain enables a physician to extract indicators, facilitating their quantitative analysis and characterization. We are investigating how estimated maps of semantic labels (obtained using machine learning techniques) can be used as a surrogate for unlabelled data. We are exploring how to combine them with multi-population deformable registration to improve both alignment and segmentation of these challenging brain structures.